Human Amniotic Membrane Dressing as a Non-Surgical Alternative for Extensive Chronic Ulcers: A Comparative Case Study

María Ximena Guerbi, Jimena María del Pilar Rodrigo, Matías Fabián Rotela, Rocío Antonella Comito, Esteban Vogel, Enrique Leo Portiansky, Alejandro Berra, Griselda Noemí Moreno, Flavia Mariana Michelini · 2026

Read Human Amniotic Membrane Dressing as a Non-Surgical Alternative for Extensive Chronic Ulcers: A Comparative Case Study by María Ximena Guerbi, Jimena María del Pilar Rodrigo, Matías Fabián Rotela, Rocío Antonella Comito, Esteban Vogel, Enrique Leo Portiansky, Alejandro Berra, Griselda Noemí Moreno, Flavia Mariana Michelini (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13256720.txt.

Description

María Ximena Guerbi and co-authors report a 2026 single-patient comparison of two dressings on different areas of one extensive chronic ulcer that had resisted standard care. One zone received a human amniotic membrane dressing, while another received a bovine collagen matrix, giving an internal control within the same wound.

After 59 days the membrane-treated zone healed so much better that clinicians extended it over the collagen area, and the whole wound closed. Tissue analysis showed quieter inflammatory signals and stronger markers of blood vessel growth and repair in the membrane zone. A single case cannot prove superiority, yet the side-by-side result supports larger trials of amniotic dressings for stubborn ulcers.

Catalog record

CREATORMaría Ximena Guerbi, Jimena María del Pilar Rodrigo, Matías Fabián Rotela, Rocío Antonella Comito, Esteban Vogel, Enrique Leo Portiansky, Alejandro Berra, Griselda Noemí Moreno, Flavia Mariana Michelini
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13256720

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