Shifting Patterns of Colorectal Cancer Burden in the United States (1999–2023): Implications for Precision Medicine Strategies and Drug Resistance in Early-Onset Colorectal Cancer
Chenyu Sun, Li Liu, Elizabeth H. Lees, Laura E. Billstein, Yuntao Zou, Abigail Fickel, Yan Yan, Yichen Wang, Tuan Vinh, Paul Travers, Vivek Kumbhari, Yuting Huang · 2026
Read Shifting Patterns of Colorectal Cancer Burden in the United States (1999–2023): Implications for Precision Medicine Strategies and Drug Resistance in Early-Onset Colorectal Cancer by Chenyu Sun, Li Liu, Elizabeth H. Lees, Laura E. Billstein, Yuntao Zou, Abigail Fickel, Yan Yan, Yichen Wang, Tuan Vinh, Paul Travers, Vivek Kumbhari, Yuting Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13255737.txt.
Description
Chenyu Sun and a large team analyzed United States colorectal cancer trends from 1999 to 2023 in a 2026 study. Overall rates have fallen thanks to screening and better treatment, yet diagnoses among younger adults keep climbing. The team broke nationwide incidence and death data down by age, sex, race, ethnicity, and geography.
Adults over fifty-five saw substantial improvement across the period. In contrast, incidence and mortality rose among younger adults, especially those under fifty-five. Black Americans and rural residents carried persistently heavier burdens than other groups. The authors connect early-onset disease to distinct tumor biology and drug resistance. They call for earlier detection, fairer access to care, and prevention tailored to younger and high-risk groups rather than one national playbook.
Catalog record
| CREATOR | Chenyu Sun, Li Liu, Elizabeth H. Lees, Laura E. Billstein, Yuntao Zou, Abigail Fickel, Yan Yan, Yichen Wang, Tuan Vinh, Paul Travers, Vivek Kumbhari, Yuting Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |