Whole-Genome Resequencing Reveals Deep Genomic Differentiation and Highly Differentiated Segments Between a Composite Domestic Cattle Population and Yak from the Ili River Valley and Other Xinjiang Regions
Guzalnur Amat, Bo Hu, Yong Tuo, Adiljan Kader, Ablat Sulayman, Zhenghong Zhan, Jianping Zhu, Zhijun Zhang, Bayin Bate, Ziyi Ren, Amat Mamat, Akida Tursun, Tongjun Guo · 2026
Read Whole-Genome Resequencing Reveals Deep Genomic Differentiation and Highly Differentiated Segments Between a Composite Domestic Cattle Population and Yak from the Ili River Valley and Other Xinjiang Regions by Guzalnur Amat, Bo Hu, Yong Tuo, Adiljan Kader, Ablat Sulayman, Zhenghong Zhan, Jianping Zhu, Zhijun Zhang, Bayin Bate, Ziyi Ren, Amat Mamat, Akida Tursun, Tongjun Guo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13255603.txt.
Description
Amat and colleagues sequenced whole genomes from seventy-nine cattle and yak in China's Ili River Valley and wider Xinjiang to map how deeply the two diverge. Six cattle groups, including introduced Angus and local Kazakh cattle, were pooled into one composite population and compared with ten yak. The team scanned for differentiation, diversity, and demographic history.
Differentiation was extreme across most of the genome, reflecting ancient species divergence rather than recent selection. A smaller set of highly differentiated segments stood out, longest on five chromosomes, enriched for genes tied to reproduction, hormone regulation, daily rhythms, and membrane transport. Yak showed the slowest linkage disequilibrium decay. The results frame regional conservation and breeding decisions.
Catalog record
| CREATOR | Guzalnur Amat, Bo Hu, Yong Tuo, Adiljan Kader, Ablat Sulayman, Zhenghong Zhan, Jianping Zhu, Zhijun Zhang, Bayin Bate, Ziyi Ren, Amat Mamat, Akida Tursun, Tongjun Guo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |