Antibacterial and anti-biofilm effects of postbiotic mediator derived from Jeotgal isolate Lactiplantibacillus plantarum KMC12 against Streptococcus mutans

Hyunjin Oh, Jihoon Kim, Jaewoo Bai · 2026

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Description

Hyunjin Oh, Jihoon Kim, and Jaewoo Bai test a bacterial product against tooth decay germs in a 2026 study. Streptococcus mutans builds the biofilm that drives dental caries. The team made a neutralized postbiotic mediator from a Lactiplantibacillus plantarum strain taken from jeotgal, a fermented seafood.

The product damaged germ membranes, causing about 87 percent damage at the top dose tested. It cut biofilm formation by 83 percent at that dose and lowered output of the glue-like coating germs use to stick. Key biofilm genes were turned down, and human gut cells showed no toxicity in tests.

Catalog record

CREATORHyunjin Oh, Jihoon Kim, Jaewoo Bai
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36911
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13255195

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