MorphoGrad: A MATLAB toolbox for simulating steady-state morphogen gradients under cell-to-cell variability
Jan A Adelmann, Roman Vetter, Dagmar Iber · 2026
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Description
Jan A. Adelmann and co-authors present MorphoGrad, a 2026 software protocol for simulating morphogen gradients, the chemical signals that pattern growing tissues. Real tissues vary from cell to cell, and that noise affects how precise a pattern can be. Their MATLAB toolbox builds that variability directly into the simulation.
The protocol walks users through setting up one- or two-dimensional tissues made of discrete cells, each with its own parameter values drawn from realistic distributions. It then covers boundary conditions, solver choices, and ways to measure how steady the resulting gradients are. The method grows out of earlier work by members of the team. For developmental biologists, the toolbox offers a shared, repeatable way to ask how much cell-level noise a patterning system can tolerate.
Catalog record
| CREATOR | Jan A Adelmann, Roman Vetter, Dagmar Iber |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |