Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy

Anna C Prins, Raymond de Boer, András G Zolnay, Remi A Nout, Mischa S Hoogeman, Kelvin Ng Wei Siang · 2026

Read Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy by Anna C Prins, Raymond de Boer, András G Zolnay, Remi A Nout, Mischa S Hoogeman, Kelvin Ng Wei Siang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13255043.txt.

Description

Anna C. Prins and colleagues present a 2026 treatment-planning study for vulvar cancer, comparing proton therapy against a standard photon technique. Patients receiving photon radiation for this cancer often suffer severe skin, urinary, bowel, and blood side effects. Protons can stop inside the body, which in theory spares healthy tissue beyond the tumor.

The cohort covered 30 patients treated at Erasmus Medical Center in Rotterdam with advanced or recurrent disease. For each patient, the team built both proton and photon plans and compared doses to organs at risk, along with estimated complication chances. No earlier planning studies had tested protons for this cancer. The authors aim to show whether the expected sparing is real enough to guide bringing proton treatment into the clinic.

Catalog record

CREATORAnna C Prins, Raymond de Boer, András G Zolnay, Remi A Nout, Mischa S Hoogeman, Kelvin Ng Wei Siang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13255043

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