Development and validation of a clinical scoring system for the prediction of methotrexate treatment response in rheumatoid arthritis patients: a multicenter real-world study
Rudy Hidayat, Fara Fauzia, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Radiyati Umi Partan, Putri Muthia, Ika Vemilia Warlisti, Bantar Suntoko, Mirza Zaka Pratama, Cesarius Singgih Wahono, Lita Diah Rahmawati, Pande Ketut Kurniari, Anggarda Kristianti Utomo, Najirman Najirman, Eka Kurniawan, Yulyani Werdiningsih, Faridin Pango, Mochammad Alfansyah Dhifanra, Jessica Audrey, Faisal Parlindungan · 2026
Read Development and validation of a clinical scoring system for the prediction of methotrexate treatment response in rheumatoid arthritis patients: a multicenter real-world study by Rudy Hidayat, Fara Fauzia, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Radiyati Umi Partan, Putri Muthia, Ika Vemilia Warlisti, Bantar Suntoko, Mirza Zaka Pratama, Cesarius Singgih Wahono, Lita Diah Rahmawati, Pande Ketut Kurniari, Anggarda Kristianti Utomo, Najirman Najirman, Eka Kurniawan, Yulyani Werdiningsih, Faridin Pango, Mochammad Alfansyah Dhifanra, Jessica Audrey, Faisal Parlindungan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13254140.txt.
Description
Rudy Hidayat and a large team build a scoring system for arthritis drug response in a 2026 multicenter study. Methotrexate is the anchor drug for rheumatoid arthritis, yet response varies widely. The team studied newly diagnosed patients on methotrexate alone and defined success as remission or low disease activity at six months.
The development group held 840 patients. Four factors predicted success: age over 60, a normal sedimentation rate, lower starting disease activity, and lower steroid dose. In a separate group of 265 patients, the score kept modest accuracy, with an AUC of 0.63. The authors offer it for early risk sorting.
Catalog record
| CREATOR | Rudy Hidayat, Fara Fauzia, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Radiyati Umi Partan, Putri Muthia, Ika Vemilia Warlisti, Bantar Suntoko, Mirza Zaka Pratama, Cesarius Singgih Wahono, Lita Diah Rahmawati, Pande Ketut Kurniari, Anggarda Kristianti Utomo, Najirman Najirman, Eka Kurniawan, Yulyani Werdiningsih, Faridin Pango, Mochammad Alfansyah Dhifanra, Jessica Audrey, Faisal Parlindungan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35545 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |