A high-resolution 3D genome map of kiwifruit provides insights into chromatin architecture and transcriptional activity
Shuangling Xie, Tong Li, Jing Yang, Jingrui Wang, Jinli Gong, Minghui Wang, Xiaoli Hu, Xiaolong Li, Xuepeng Sun · 2026
Read A high-resolution 3D genome map of kiwifruit provides insights into chromatin architecture and transcriptional activity by Shuangling Xie, Tong Li, Jing Yang, Jingrui Wang, Jinli Gong, Minghui Wang, Xiaoli Hu, Xiaolong Li, Xuepeng Sun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13253338.txt.
Description
Shuangling Xie and colleagues build a three-dimensional genome atlas of kiwifruit in a 2026 study. Genes are controlled partly by how DNA folds inside the nucleus, but detailed folding maps existed for few perennial fruit crops. The team used a chromosome capture technique to chart contacts across the kiwifruit genome in leaf and fruit tissue.
They layered the folding maps with data on chromatin accessibility, DNA methylation, seven histone marks, and gene activity across tissues and fruit development stages. The combined resource annotates architecture at nested scales, from large active and silent compartments down to small domains and individual loops. The broad layout proved similar between leaf and fruit, while finer features such as domain insulation and loop frequency varied in quantity. The authors offer the atlas as a reference for breeding and functional studies in kiwifruit and other woody perennials.
Catalog record
| CREATOR | Shuangling Xie, Tong Li, Jing Yang, Jingrui Wang, Jinli Gong, Minghui Wang, Xiaoli Hu, Xiaolong Li, Xuepeng Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |