Evaluation of two point-of-care molecular diagnostic platforms for rapid detection of equine Hendra virus
Lyndal Hulse, Leonard Izzard, Singanallur Balasubramanian Nagendrakumar, Axel Colling, Darren Underwood, Luke Driver, David T. Williams, Benjamin Ahern · 2026
Read Evaluation of two point-of-care molecular diagnostic platforms for rapid detection of equine Hendra virus by Lyndal Hulse, Leonard Izzard, Singanallur Balasubramanian Nagendrakumar, Axel Colling, Darren Underwood, Luke Driver, David T. Williams, Benjamin Ahern (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13253132.txt.
Description
Lyndal Hulse and colleagues evaluate two rapid molecular platforms for detecting Hendra virus in horses in a 2026 study. Hendra is a lethal virus endemic to eastern Australia that spreads from bats to horses and can kill people who handle sick animals. A trustworthy field test would let veterinarians act before laboratory confirmation arrives.
The team compared a standard real-time PCR test with an isothermal amplification method designed for simpler field use. The PCR test proved far more sensitive, detecting a single copy of viral material per microliter against a thousand copies for the rival method, so the weaker platform was dropped early. Statistical modeling estimated the PCR test's accuracy on field-style samples prepared with a quick extraction-free method. The authors judge PCR with rapid sample preparation a feasible first-line field tool for ruling Hendra in or out.
Catalog record
| CREATOR | Lyndal Hulse, Leonard Izzard, Singanallur Balasubramanian Nagendrakumar, Axel Colling, Darren Underwood, Luke Driver, David T. Williams, Benjamin Ahern |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |