Stem cell-based scaffolds using dental pulp and adipose-derived stem cells in periodontal regeneration: Evidence from preclinical or clinical studies

Manimekalai Muthusamy, Beena George, Divya Alexander, Siladitya Sen, Suma Janya, Bindu Devanahalli Rajanna · 2026

Read Stem cell-based scaffolds using dental pulp and adipose-derived stem cells in periodontal regeneration: Evidence from preclinical or clinical studies by Manimekalai Muthusamy, Beena George, Divya Alexander, Siladitya Sen, Suma Janya, Bindu Devanahalli Rajanna (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13252327.txt.

Description

Manimekalai Muthusamy and co-authors review stem cell scaffolds for gum disease repair in a 2026 article. Standard care cannot reliably rebuild the bone, ligament, and cement lost to periodontal disease. Scaffolds seeded with stem cells from dental pulp or from fat offer a living route to coordinated regrowth.

Animal studies in the review show more new bone, cement-like layers, and ordered ligament fibres than scaffold-only controls. Blood vessel growth also improved in the treated defects. Early clinical reports add shallower probing depths, gains in attachment, and good safety. The authors caution that standard protocols and long-term data are still thin, so firm clinical claims must wait.

Catalog record

CREATORManimekalai Muthusamy, Beena George, Divya Alexander, Siladitya Sen, Suma Janya, Bindu Devanahalli Rajanna
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE14 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13252327

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