Post-operative pain in molar teeth with symptomatic apical periodontitis using cryotreated neem extract and cryotreated 2.5% sodium hypochlorite: A randomised double-blinded clinical trial

Ruchi Vashisht, Umesh Kumar, Ashish Kumar Kakkar, Om Parkash Katare, Umesh Kumar Patil, Prabhleen Kaur Brar · 2026

Read Post-operative pain in molar teeth with symptomatic apical periodontitis using cryotreated neem extract and cryotreated 2.5% sodium hypochlorite: A randomised double-blinded clinical trial by Ruchi Vashisht, Umesh Kumar, Ashish Kumar Kakkar, Om Parkash Katare, Umesh Kumar Patil, Prabhleen Kaur Brar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13252313.txt.

Description

Ruchi Vashisht, Umesh Kumar, Ashish Kumar Kakkar, and three colleagues test chilled irrigation for root canal pain in this two thousand twenty-six randomized, double-blinded trial. Pain after root canal treatment remains a key concern. The trial enrolled one hundred eight patients with painful apical periodontitis in molar teeth, all treated in a single visit. Four irrigation groups compared room-heat against chilled sodium hypochlorite, and room-heat against chilled neem extract, a plant choice.

Pain was scored on a visual scale at twenty-four hours, forty-eight hours, and seven days. Chilled irrigants produced clearly lower pain at the first two time points than their room-heat matches. Neem extract performed about as well as chilled sodium hypochlorite. The authors conclude chilled neem extract is a biocompatible irrigant for cutting pain after treatment, pairing cooling with a natural product patients may prefer over bleach.

Catalog record

CREATORRuchi Vashisht, Umesh Kumar, Ashish Kumar Kakkar, Om Parkash Katare, Umesh Kumar Patil, Prabhleen Kaur Brar
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13252313

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