Predictive value of extra-rectal colonization and the Giannella risk score for subsequent carbapenem-resistant Enterobacterales infections in ICU patients: an Argentinean retrospective cohort study in a mixed KPC and NDM setting
P. Favier, P. Suárez-Urquiza, C. Raffo, D. Torres, F. Pinilla-Huayta, C. Muñoz-Soto, M. Ravelli, E. Serio, L. Kumar, P. Johanna, I. Primost, M.I. Gallino, J. Pemán-García, A. Valentín-Martín, E.M. González-Barberá · 2026
Read Predictive value of extra-rectal colonization and the Giannella risk score for subsequent carbapenem-resistant Enterobacterales infections in ICU patients: an Argentinean retrospective cohort study in a mixed KPC and NDM setting by P. Favier, P. Suárez-Urquiza, C. Raffo, D. Torres, F. Pinilla-Huayta, C. Muñoz-Soto, M. Ravelli, E. Serio, L. Kumar, P. Johanna, I. Primost, M.I. Gallino, J. Pemán-García, A. Valentín-Martín, E.M. González-Barberá (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13251657.txt.
Description
Favier and co-authors test two warning signs for drug-resistant gut infections in intensive care patients. Carbapenem-resistant Enterobacterales are spreading through two enzyme families, KPC and NDM, and doctors need to know which colonized patients will turn infected. The Argentine team followed three hundred twenty-seven rectally colonized ICU patients for up to ninety days, during a local outbreak.
About one in nine developed infection. Carriage of the bacteria at extra-rectal sites independently raised that risk more than threefold, and it was highly specific though insensitive, missing most future cases. The Giannella risk score performed only moderately overall and poorly when split by enzyme type. The authors conclude neither tool alone suffices to steer early therapy in mixed settings like theirs.
Catalog record
| CREATOR | P. Favier, P. Suárez-Urquiza, C. Raffo, D. Torres, F. Pinilla-Huayta, C. Muñoz-Soto, M. Ravelli, E. Serio, L. Kumar, P. Johanna, I. Primost, M.I. Gallino, J. Pemán-García, A. Valentín-Martín, E.M. González-Barberá |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |