Clinical and Sociodemographic Correlates of Poor Medication Adherence in People With Bipolar Disorder: A Systematic Review and Meta‐Analysis
Francesco Bartoli, Daniele Cavaleri, Ilaria Riboldi, Chiara Alessandra Capogrosso, Carlo Bassetti, Marco Broccia, Giorgio Cucchi, Cristina Crocamo, Martha Sajatovic, Giuseppe Carrà · 2026
Read Clinical and Sociodemographic Correlates of Poor Medication Adherence in People With Bipolar Disorder: A Systematic Review and Meta‐Analysis by Francesco Bartoli, Daniele Cavaleri, Ilaria Riboldi, Chiara Alessandra Capogrosso, Carlo Bassetti, Marco Broccia, Giorgio Cucchi, Cristina Crocamo, Martha Sajatovic, Giuseppe Carrà (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13251348.txt.
Description
Bartoli and colleagues pooled the evidence in 2026 on what marks out people with bipolar disorder who take their medicines poorly, a pattern that feeds relapse. Their systematic review searched major databases to March 2025 and combined results across studies with random-effects models, expressing links as odds ratios or standardized differences.
Nineteen studies qualified. Poor adherence tracked with younger age, less schooling, not being in a relationship, and earlier illness onset. Psychotic features, past suicide attempts, more manic and mixed episodes, and more hospital stays also raised the odds. Cannabis and alcohol use disorders, added anxiety and personality disorders, lower insight, and worse overall functioning all clustered in the poorly adherent group. The authors caution that effects were small and the evidence uneven, yet say the profile can help clinics spot patients who need adherence support most.
Catalog record
| CREATOR | Francesco Bartoli, Daniele Cavaleri, Ilaria Riboldi, Chiara Alessandra Capogrosso, Carlo Bassetti, Marco Broccia, Giorgio Cucchi, Cristina Crocamo, Martha Sajatovic, Giuseppe Carrà |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |