Calprotectin as a Diagnostic Marker for Lower Respiratory Tract Infection and Sepsis in the Emergency Department
Martin Wollmer, Torgny Wessman, Olle Melander, Anders Larsson, Toralph Ruge · 2026
Read Calprotectin as a Diagnostic Marker for Lower Respiratory Tract Infection and Sepsis in the Emergency Department by Martin Wollmer, Torgny Wessman, Olle Melander, Anders Larsson, Toralph Ruge (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13251339.txt.
Description
Martin Wollmer and colleagues tested a blood marker called calprotectin for sorting out sepsis in the emergency department, reporting in 2026. Calprotectin is released by activated neutrophils, a type of white blood cell that fights infection. The team wanted to know whether it could separate true sepsis from similar inflammation and pinpoint where an infection sits.
Plasma taken at arrival was analyzed for 583 patients with suspected sepsis at a university hospital in southern Sweden. On its own the marker separated sepsis from noninfectious inflammation only modestly, and it added nothing once the standard marker CRP was counted. Its real value appeared in locating the infection source. Adding calprotectin to CRP sharpened the contrast between chest infections and both upper airway and urinary infections. The authors say further work must show whether it improves on ordinary clinical judgment.
Catalog record
| CREATOR | Martin Wollmer, Torgny Wessman, Olle Melander, Anders Larsson, Toralph Ruge |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |