Programmable DNAzyme nanocatalysts orchestrate redox-immune coupling for time-gated cancer immunomodulation

Lu Wang, Rongping Luo, Lingxiu Zou, Xiaojing Liu, Zhuojia Tang, Fengqi Dong, Zhen Wang, Jianxin Lyu, Yi Zhang · 2026

Read Programmable DNAzyme nanocatalysts orchestrate redox-immune coupling for time-gated cancer immunomodulation by Lu Wang, Rongping Luo, Lingxiu Zou, Xiaojing Liu, Zhuojia Tang, Fengqi Dong, Zhen Wang, Jianxin Lyu, Yi Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13251222.txt.

Description

Immune activation within tumors is governed by highly dynamic redox and mitochondrial signaling events, yet the temporal organization of these processes remains poorly defined. Here, we report a programmable DNAzyme nanocatalyst (APTZ) that enables time-dependent redox-immune coupling by translating intracellular catalytic activity into a transient biochemical signal window.

Catalog record

CREATORLu Wang, Rongping Luo, Lingxiu Zou, Xiaojing Liu, Zhuojia Tang, Fengqi Dong, Zhen Wang, Jianxin Lyu, Yi Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE55 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13251222

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