Enhanced periodontal regeneration using formulated injectable hyaluronic acid with or without PRP: A rat ligature model
Wafaa Yahia Alghonemy, Nevien M Ahmed, Abeer A Abou Samra, Omnia M Abdelfatah, Rania A Hanafy, Asmaa M Abd El-Aziz, Eman M Salem · 2026
Read Enhanced periodontal regeneration using formulated injectable hyaluronic acid with or without PRP: A rat ligature model by Wafaa Yahia Alghonemy, Nevien M Ahmed, Abeer A Abou Samra, Omnia M Abdelfatah, Rania A Hanafy, Asmaa M Abd El-Aziz, Eman M Salem (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13251205.txt.
Description
Wafaa Yahia Alghonemy and co-authors tested injectable treatments for gum disease in rats, reporting in 2026. Periodontitis destroys the tissues and bone that hold teeth, driven by bacteria and the body's inflammatory response. The team compared hyaluronic acid gel, platelet-rich plasma from the animals' own blood, and the two combined.
Forty male rats with wire-induced gum disease were divided into five groups, including healthy and untreated controls. After two weeks, treated animals showed less tissue damage under the microscope than untreated ones. Blood markers of inflammation, two signals known as TNF-alpha and IL-1beta, also fell with treatment. The combined gel and plasma group healed best, while each treatment alone gave partial recovery. The authors suggest the pairing strengthens both the calming of inflammation and the rebuilding of tissue, though they call for further study.
Catalog record
| CREATOR | Wafaa Yahia Alghonemy, Nevien M Ahmed, Abeer A Abou Samra, Omnia M Abdelfatah, Rania A Hanafy, Asmaa M Abd El-Aziz, Eman M Salem |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |