Variation of rabbit serum IgA in relation to RHDV vaccination and infection: implications for serological diagnosis and epidemiological investigations
Lorenzo Capucci, Vittoria Di Giovanni, Michele Schiavitto, Patrizia Cavadini, Antonio Lavazza, Brian Cooke · 2026
Read Variation of rabbit serum IgA in relation to RHDV vaccination and infection: implications for serological diagnosis and epidemiological investigations by Lorenzo Capucci, Vittoria Di Giovanni, Michele Schiavitto, Patrizia Cavadini, Antonio Lavazza, Brian Cooke (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13251028.txt.
Description
Capucci and colleagues clarify a confusing blood marker in rabbits vaccinated or infected with hemorrhagic disease virus. Their 2026 Veterinary Research study combines two vaccination experiments with a three-month farm watch during an unexpected outbreak. Antibody readings in rabbits are widely used, but the IgA class was hard to interpret.
Vaccination alone produced only traces of IgA for a few weeks in about half the rabbits. A real oral challenge, by contrast, triggered a marked and rapid IgA rise in the animals. On the farm, steady IgA marked the oldest does, survivors of an earlier epidemic, and new positives appeared with the outbreak. The authors conclude that IgA works as a sign of reinfection rather than of vaccination.
Catalog record
| CREATOR | Lorenzo Capucci, Vittoria Di Giovanni, Michele Schiavitto, Patrizia Cavadini, Antonio Lavazza, Brian Cooke |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |