Defining the Minimal Clinically Important Difference and Patient Acceptable Symptom State for Isolated Microfracture of the Knee at 5-Year Follow-up
Rodrigo Saad Berreta, Zeeshan A. Khan, Sachin Allahabadi, Joshua Wright-Chisem, Jonathan Spaan, Jared Rubin, Juan Bernardo Villarreal-Espinosa, Adam B. Yanke, Brian Forsythe, Nikhil N. Verma, Jorge Chahla, Brian J. Cole · 2026
Read Defining the Minimal Clinically Important Difference and Patient Acceptable Symptom State for Isolated Microfracture of the Knee at 5-Year Follow-up by Rodrigo Saad Berreta, Zeeshan A. Khan, Sachin Allahabadi, Joshua Wright-Chisem, Jonathan Spaan, Jared Rubin, Juan Bernardo Villarreal-Espinosa, Adam B. Yanke, Brian Forsythe, Nikhil N. Verma, Jorge Chahla, Brian J. Cole (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13250429.txt.
Description
Saad Berreta and a large team define how much improvement actually matters to patients after knee microfracture surgery. Their 2026 Orthopaedic Journal of Sports Medicine study follows seventy patients treated for cartilage defects between 2013 and 2018. Outcomes were tracked for at least five years using standard knee function scores.
The team set two kinds of thresholds: the smallest change patients can feel, and the score level where symptoms feel acceptable. Roughly two thirds of patients reached the meaningful-change threshold on most scores, and about half reached an acceptable state. Starting with worse scores made meaningful change more likely, while lower body weight, milder joint wear, and smaller lesions favored acceptable outcomes. The thresholds give future trials a fair yardstick for judging success.
Catalog record
| CREATOR | Rodrigo Saad Berreta, Zeeshan A. Khan, Sachin Allahabadi, Joshua Wright-Chisem, Jonathan Spaan, Jared Rubin, Juan Bernardo Villarreal-Espinosa, Adam B. Yanke, Brian Forsythe, Nikhil N. Verma, Jorge Chahla, Brian J. Cole |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |