Colonic Perineurioma Presenting as a Small Subepithelial Lesion With Distinctive Endoscopic Findings
Hironobu Takedomi, Moeko Shirozu, Kayoko Fukuda, Takashi Yao, Motohiro Esaki · 2026
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Description
Takedomi and colleagues report a tiny benign nerve sheath tumor found during a screening colonoscopy. Their DEN Open case concerns a fifty-nine-year-old man with a past colon polyp removal. Doctors spotted a small reddish, slightly raised spot in his sigmoid colon, with a smooth surface and clear edges.
Magnified imaging showed widened round pits, sparse crypts, and branching vessels at the center of the lesion. The spot was removed with a cold snare, serving both diagnosis and treatment in one step. Microscope and staining tests identified a colonic perineurioma, a rare harmless tumor of nerve-wrapping cells. The authors advise keeping this tumor in mind for small under-surface colon lesions, while noting that only tissue tests can confirm it.
Catalog record
| CREATOR | Hironobu Takedomi, Moeko Shirozu, Kayoko Fukuda, Takashi Yao, Motohiro Esaki |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 8 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |