Engineered Nanomaterials for Drug Delivery in Temporomandibular Joint Osteoarthritis: Translational Insights and Current Advances
Shoufu Sun, Yunan Jiang, Jichun Zhang, Shanyong Zhang, Yuanjin Xu · 2026
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Description
Sun and colleagues review tiny engineered carriers that could deliver drugs straight into the jaw joint. Their 2026 International Journal of Nanomedicine paper covers temporomandibular joint osteoarthritis, where cartilage breaks down and the joint lining stays inflamed. Standard treatments reach the joint poorly and wash out quickly, limiting their benefit.
The review surveys liposomes, polymer particles, micelles, metal-organic frameworks, and hydrogels designed to stay longer and release drugs slowly or on cue. Newer materials such as nanozymes may also calm inflammation and help cartilage repair. The authors caution that most evidence comes from other joints, not the jaw itself. They call for jaw-specific testing, smarter responsive systems, and standard ways to judge results.
Catalog record
| CREATOR | Shoufu Sun, Yunan Jiang, Jichun Zhang, Shanyong Zhang, Yuanjin Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |