Comparing bridging drug therapy approaches prior to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: a prospective analysis from the national UK CURATE registry
Oliver M Li, Hakim Ghani, Paula Appenzeller, Liliana Amaral-Almeida, Paul Bambrough, John E Cannon, Dolores Taboada, Katherine L Bunclark, Mark Toshner, Karen Sheares, John G Coghlan, Joanna Pepke-Zaba, Stephen P Hoole · 2026
Read Comparing bridging drug therapy approaches prior to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: a prospective analysis from the national UK CURATE registry by Oliver M Li, Hakim Ghani, Paula Appenzeller, Liliana Amaral-Almeida, Paul Bambrough, John E Cannon, Dolores Taboada, Katherine L Bunclark, Mark Toshner, Karen Sheares, John G Coghlan, Joanna Pepke-Zaba, Stephen P Hoole (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13250194.txt.
Description
Li and co-authors compare drug treatments given before a balloon procedure for a serious form of high blood pressure in the lungs. Their 2026 Open Heart paper uses the United Kingdom's national registry for chronic thromboembolic pulmonary hypertension. Patients received medicines to lower lung artery pressure before balloon pulmonary angioplasty at one national center.
Among one hundred fifty-eight patients, those on two-drug therapy started sicker, with higher pressures and lower heart output. They also improved the most before the procedure, gaining more heart output and dropping resistance further than single-drug groups. Complication rates at the first balloon procedure were similar across the strategies. Lung injury was more common in patients who still had very high pressures at procedure time.
Catalog record
| CREATOR | Oliver M Li, Hakim Ghani, Paula Appenzeller, Liliana Amaral-Almeida, Paul Bambrough, John E Cannon, Dolores Taboada, Katherine L Bunclark, Mark Toshner, Karen Sheares, John G Coghlan, Joanna Pepke-Zaba, Stephen P Hoole |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |