THE IL-6/IL-10 INFLAMMATORY AXIS AND PROGNOSIS OF CIRRHOSIS-ASSOCIATED HEPATOCELLULAR CARCINOMA: A NARRATIVE REVIEW
Rubens Barbosa REZENDE · 2026
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Description
Rezende reviewed two immune messengers as outlook markers in liver cancer, in a 2026 narrative review. Hepatocellular carcinoma usually grows in a scarred, cirrhotic liver, where chronic inflammation feeds the tumor. Searching literature from 2010 to 2025, the author weighed studies of interleukin-6, which drives inflammation, and interleukin-10, which calms it, in patients' blood.
Raised interleukin-6 consistently accompanied bigger tumor burden and poorer survival after both drug and local therapies. Interleukin-10 also ran high in many patients, but its meaning shifted with disease stage and tumor surroundings. The author calls for standard test methods and shared cut-off values before either marker guides everyday decisions.
Catalog record
| CREATOR | Rubens Barbosa REZENDE |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |