The microbiome-inflammation-immune axis in oral squamous cell carcinoma: from mechanistic insights to therapeutic perspectives
Zhongjun Wang, QingYuan Bian, Yue Chu, Wanyue Zhu, Ying Qin, Jiwei Zheng · 2026
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Description
Zhongjun Wang and co-authors frame mouth cancer growth around a three-way axis in a 2026 review. Oral squamous cell carcinoma is the most common head and neck cancer. Most research treats microbe shifts, inflammation, and immunity as separate stories.
The review joins them: disturbed mouth microbes can spark inflammation, which then reshapes the immune setting around a tumor. Signal paths switched on by microbe sensing help drive that chain. The authors also gather clinical markers from blood and saliva that reflect each leg of the axis. Such combined markers could aid early detection and choice of care. The axis is offered as a working idea to test.
Catalog record
| CREATOR | Zhongjun Wang, QingYuan Bian, Yue Chu, Wanyue Zhu, Ying Qin, Jiwei Zheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |