Comprehensive analysis of efferocytosis-related genes in diagnosis and immune infiltration in atherosclerosis: based on bulk and single-cell RNA sequencing data
Jintao Qian, Junhao Zhang, Jiahui Wang, Suyu Xu, Li Yu, Chuiyu Kong, Qing Zhou · 2026
Read Comprehensive analysis of efferocytosis-related genes in diagnosis and immune infiltration in atherosclerosis: based on bulk and single-cell RNA sequencing data by Jintao Qian, Junhao Zhang, Jiahui Wang, Suyu Xu, Li Yu, Chuiyu Kong, Qing Zhou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13246637.txt.
Description
Jintao Qian and co-authors hunt genes tied to clean-up of dead cells in artery disease in a 2026 analysis. The clean-up process, called efferocytosis, keeps tissue stable, and its failure feeds atherosclerosis. Which genes drive it inside plaque cells was only partly known.
Joining bulk and single-cell gene data, the team found six core genes with strong power to separate patients from controls. Macrophages, muscle cells, and lining cells all played roles in the clean-up work. Patient scores built on the six genes split the disease into two molecular types. Lab blots confirmed the gene products appear in diseased tissue. The set could guide sharper diagnosis and subtyping.
Catalog record
| CREATOR | Jintao Qian, Junhao Zhang, Jiahui Wang, Suyu Xu, Li Yu, Chuiyu Kong, Qing Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |