Clove (Syzygium aromaticum) and its bioactive constituent eugenol alleviate psoriatic inflammation by modulating the IL-36/IL-17A axis: a proteomic and mechanistic study
Tin-Yun Ho, Hsin-Yi Lo, Chiao-Che Chen, Hui-Chi Huang, Chien-Yun Hsiang · 2026
Read Clove (Syzygium aromaticum) and its bioactive constituent eugenol alleviate psoriatic inflammation by modulating the IL-36/IL-17A axis: a proteomic and mechanistic study by Tin-Yun Ho, Hsin-Yi Lo, Chiao-Che Chen, Hui-Chi Huang, Chien-Yun Hsiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13246417.txt.
Description
Tin-Yun Ho and co-authors test clove and its main compound against psoriasis-like skin disease in mice in 2026 work. Clove has a folk history for inflamed skin, but its targets in psoriasis were vague. Eugenol makes up about two thirds of clove extract.
Mice with induced skin disease got oral clove extract or eugenol and improved visibly. Scaling eased and skin thickening shrank under treatment. Protein mapping showed the pair calmed two linked inflammation paths and raised a natural brake protein. Bench tests showed they also block a key immune signal from docking with its receptor. The dual action may explain the skin gains.
Catalog record
| CREATOR | Tin-Yun Ho, Hsin-Yi Lo, Chiao-Che Chen, Hui-Chi Huang, Chien-Yun Hsiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |