Systemic immune responses in patients with spine surgery related infections

Pia Fehrenbach, Siegmund Lang, Maja Gocević, Puk Kwant, Daniel Haschtmann, Tamas F. Fekete, Ursula Menzel, Esther C. de Jong, T. Fintan Moriarty, Sibylle Grad, Markus Loibl · 2026

Read Systemic immune responses in patients with spine surgery related infections by Pia Fehrenbach, Siegmund Lang, Maja Gocević, Puk Kwant, Daniel Haschtmann, Tamas F. Fekete, Ursula Menzel, Esther C. de Jong, T. Fintan Moriarty, Sibylle Grad, Markus Loibl (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13246327.txt.

Description

Pia Fehrenbach and colleagues profile blood immune cells in patients infected after spine surgery in 2026 work. Infections at the surgical site are a feared outcome, yet the body-wide immune reply in spine cases is poorly charted. Better maps could yield tests or treatments.

The team compared 17 infected patients with 20 matched patients who healed cleanly. Deep cell profiling found 46 cell clusters, and 30 differed between the groups. Infected patients carried fewer natural killer cells and fewer of one dendritic cell type. Several activated T cell types ran higher instead. Certain cell counts separated the groups well enough to hint at a blood test for early detection.

Catalog record

CREATORPia Fehrenbach, Siegmund Lang, Maja Gocević, Puk Kwant, Daniel Haschtmann, Tamas F. Fekete, Ursula Menzel, Esther C. de Jong, T. Fintan Moriarty, Sibylle Grad, Markus Loibl
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13246327

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