The multifaceted role of FAM13A in pulmonary diseases
Zhengqiang Luo, Keyan Lu, Mingqian Lai, Sixuan Liang, Guoda Ma, Yajun Wang · 2026
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Description
Zhengqiang Luo and co-authors review one gene's split personality across lung diseases in a 2026 synthesis. The gene, FAM13A, sits mostly in lung tissue and helps steer cell growth signals. It has been tied to chronic bronchitis-type disease, scarring, asthma, and lung cancer alike.
Oddly, the gene seems to drive tissue loss in one disease yet soften scarring in another. Many gene variants and species gaps in expression make the picture harder to read. Environment also shifts what the gene does. The review joins genetic, molecular, and functional proof into one framework. It ends by mapping what precision lung medicine still needs to learn about this gene.
Catalog record
| CREATOR | Zhengqiang Luo, Keyan Lu, Mingqian Lai, Sixuan Liang, Guoda Ma, Yajun Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |