Investigating the gut microbiota in advanced heart failure and cardiac cachexia
Mansimran Singh Dulay, Despoina Chrysostomou, Monica Campos, Marko Storch, Lauren A Roberts, Damanpreet Singh Dev, Nahal Raza, Ramey Assaf, Tricia Tan, Michael Marber, Rakesh Sharma, Thomas Lüscher, Julian R Marchesi, Owais Dar · 2026
Read Investigating the gut microbiota in advanced heart failure and cardiac cachexia by Mansimran Singh Dulay, Despoina Chrysostomou, Monica Campos, Marko Storch, Lauren A Roberts, Damanpreet Singh Dev, Nahal Raza, Ramey Assaf, Tricia Tan, Michael Marber, Rakesh Sharma, Thomas Lüscher, Julian R Marchesi, Owais Dar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13245056.txt.
Description
Mansimran Singh Dulay and colleagues gave cardiac cachexia its first gut-microbe study, asking whether the wasting syndrome of advanced heart failure has a microbial mark. Their study appeared in Gut Microbes Reports in 2026. Patients with advanced failure, with and without cachexia, plus stable patients and healthy controls, returned stool samples for sequencing. Sixty-seven samples came back, fourteen from the cachexia group.
No bacterial group cleanly separated the cachexia patients from the rest, though a weak trend toward a different overall community structure appeared. Right-heart dysfunction made no microbial difference either. Across the wider heart failure spectrum, though, clear shifts showed up, including in Streptococcus, Alistipes, and Bacteroides. The authors read cachexia's gut signal as subtle at most and call for much larger cohorts. Heart failure does reshape the gut; the wasting stage may add no signature of its own.
Catalog record
| CREATOR | Mansimran Singh Dulay, Despoina Chrysostomou, Monica Campos, Marko Storch, Lauren A Roberts, Damanpreet Singh Dev, Nahal Raza, Ramey Assaf, Tricia Tan, Michael Marber, Rakesh Sharma, Thomas Lüscher, Julian R Marchesi, Owais Dar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |