Impact of guideline definitions on right ventricular diameter in echocardiography: an automated analysis in controls and patients with pulmonary hypertension
Frida N. Hermansson, Bettia E. Celestin, Shadi P. Bagherzadeh, Gracia Fahed, Everton J. Santana, Neha Mantri, Roham T. Zamanian, Alison L. Marsden, Seraina A. Dual, Michael Salerno, Francois Haddad · 2026
Read Impact of guideline definitions on right ventricular diameter in echocardiography: an automated analysis in controls and patients with pulmonary hypertension by Frida N. Hermansson, Bettia E. Celestin, Shadi P. Bagherzadeh, Gracia Fahed, Everton J. Santana, Neha Mantri, Roham T. Zamanian, Alison L. Marsden, Seraina A. Dual, Michael Salerno, Francois Haddad (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13244954.txt.
Description
Frida Hermansson and colleagues show that defining a heart measurement differently changes the diagnosis. Their study appeared in Echo Research and Practice in 2026. The 2025 American heart-ultrasound guidelines redrew where right-ventricle widths are taken, replacing the 2010 rules. The team remeasured scans from 208 healthy volunteers and 221 lung-artery hypertension patients under the old rules, the new ones, and a new automated method.
The definitions did not agree. Where the calipers land shifted both the numbers and who crossed the threshold for calling the ventricle enlarged. An automated approach following the chamber's curved centerline offered a more consistent reference. The authors warn that switching versions mid-practice can manufacture apparent change in an unchanged patient. Labs, they argue, must adopt the new rules knowingly, flag the switch in reports, and read repeat scans with the ruler in mind.
Catalog record
| CREATOR | Frida N. Hermansson, Bettia E. Celestin, Shadi P. Bagherzadeh, Gracia Fahed, Everton J. Santana, Neha Mantri, Roham T. Zamanian, Alison L. Marsden, Seraina A. Dual, Michael Salerno, Francois Haddad |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |