Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence
Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi · 2026
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Description
Long Zhao and co-authors reviewed what plants that are both food and medicine can do for osteoporosis, grading the evidence plant by plant. Their scoping review appeared in Food Science and Nutrition in 2026. Sixty-one such plants and their active ingredients have been tested, mostly in animals and cells. The claimed mechanisms span estrogen-like action, antioxidant defense, gut flora tuning, and control of cell self-digestion.
The grading is sobering. Twenty-four plants rest on a single animal or cell study each, and thirty-four on several consistent animal studies. Only a handful have reached preliminary human trials, and those carry limits. Nothing in the pile supports replacing standard osteoporosis drugs. The authors position these plants as long-term adjuncts for prevention and early intervention instead. Their prescription for the field: standardized extracts and trials that count fractures, the outcome patients fear, rather than bone density alone.
Catalog record
| CREATOR | Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |