Clinical characteristics and outcomes of diabetic ketoacidosis in patients with type 2 diabetes during acute systemic stress
Rania Al Sayed Abd Albaky Mohamed, Laila Mahmoud Ali Hendawy, Eman Elsayed Mahmoud Farghaly, Amr Mahmoud Mohamed Abd El Hady Saleh · 2026
Read Clinical characteristics and outcomes of diabetic ketoacidosis in patients with type 2 diabetes during acute systemic stress by Rania Al Sayed Abd Albaky Mohamed, Laila Mahmoud Ali Hendawy, Eman Elsayed Mahmoud Farghaly, Amr Mahmoud Mohamed Abd El Hady Saleh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13244619.txt.
Description
Rania Mohamed and colleagues compared type 2 diabetes patients hospitalized with COVID-19 who did or did not develop diabetic ketoacidosis. Their case-control study appeared in Cardiovascular Diabetology - Endocrinology Reports in 2026. At an isolation hospital in Egypt, seventy patients admitted between 2021 and 2022 were split evenly between those with the acid crisis and those without. The team measured beta-cell output, risk factors, and outcomes from the records.
Insulin production, judged by C-peptide, was no lower in the crisis group, overturning the simple story of total insulin failure. Instead, those patients were older by about a decade, had lived with diabetes longer, and carried heavier inflammation and stress markers. Severe insulin resistance, not absence of insulin, sat at the center. Their hospital courses ran worse, with significantly higher illness and death. The authors call this ketoacidosis multifactorial, brewed by age, duration, resistance, and the inflammatory storm of COVID itself.
Catalog record
| CREATOR | Rania Al Sayed Abd Albaky Mohamed, Laila Mahmoud Ali Hendawy, Eman Elsayed Mahmoud Farghaly, Amr Mahmoud Mohamed Abd El Hady Saleh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |