Treatment Advances in Gynecologic Cancers: Insights From Recent Clinical Trials
Yiyang Shen, Xiaofei Jiao, Yuanjia Wen, Zikun Peng, Xuejiao Zhao, Jiahao Liu, Qinglei Gao · 2026
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Description
Yiyang Shen, Xiaofei Jiao, and Yuanjia Wen reviewed how recent clinical trials are changing the treatment of gynecologic cancers. Their review appeared in Cancer Innovation in 2026. Care has shifted toward specialist-led combinations of surgery, drugs, and radiation, yet surgeons still face hard calls in the operating room, and drug resistance and toxicity limit medical therapy. The authors sort the newest trial evidence by cancer site and strategy.
In early cervical cancer, sentinel node biopsy now looks like a safe stand-in for full lymph node removal, sparing patients much harm. In advanced ovarian cancer, upfront debulking surgery beat chemotherapy-first approaches in fit patients at expert centers. Immune therapy gains ground through paired checkpoint drugs and triple regimens, while antibody-drug conjugates aimed at two tissue targets produced lasting responses in selected patients. The review maps where precision is genuinely replacing routine.
Catalog record
| CREATOR | Yiyang Shen, Xiaofei Jiao, Yuanjia Wen, Zikun Peng, Xuejiao Zhao, Jiahao Liu, Qinglei Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |