Sex-based survival disparities persist in liver transplantation: MELD 3.0 fails to improve survival for waitlisted women

Marissa Di Napoli, Trevor Nydam, Michael Kriss, Maria Baimas-George, Bryon Bhagwandin, Bruce Kaplan, John Malamon · 2026

Read Sex-based survival disparities persist in liver transplantation: MELD 3.0 fails to improve survival for waitlisted women by Marissa Di Napoli, Trevor Nydam, Michael Kriss, Maria Baimas-George, Bryon Bhagwandin, Bruce Kaplan, John Malamon (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13243226.txt.

Description

Marissa Di Napoli and colleagues test whether a new liver scoring rule closed a sex gap in 2026. The MELD 3.0 rule, adopted in 2023, was meant to judge disease severity more fairly for women awaiting transplant. Earlier rules had left women at higher risk of dying while they waited.

The team studied 95,211 adults on the United States waitlist from 2017 to 2024. Women still faced a higher risk of death within 180 days than men under the new rule. Risk also rose steeply with age, and older patients with high scores had the worst odds of survival. The authors call for further change so the waitlist treats women more fairly.

Catalog record

CREATORMarissa Di Napoli, Trevor Nydam, Michael Kriss, Maria Baimas-George, Bryon Bhagwandin, Bruce Kaplan, John Malamon
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13243226

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