Persistent dysbiosis of intestinal and oral microbiota after neoadjuvant radiotherapy for rectal cancer: Implications for surgery and microbiome intervention
Yihao Zhang, Junze Xue, Hao Lin, Kun Wang, Xiaojie Tan, Xuelong Jiao, Haitao Jiang · 2026
Read Persistent dysbiosis of intestinal and oral microbiota after neoadjuvant radiotherapy for rectal cancer: Implications for surgery and microbiome intervention by Yihao Zhang, Junze Xue, Hao Lin, Kun Wang, Xiaojie Tan, Xuelong Jiao, Haitao Jiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13243090.txt.
Description
Yihao Zhang led this 2026 study of patients with rectal cancer who received radiation treatment before surgery. Radiation can injure the gut lining and disturb its bacteria, yet how long these changes last, and whether mouth bacteria change too, was unclear.
The team took gut tissue samples at set times after radiation and tested saliva and gut bacteria from 18 patients, nine in each group. One immune signal stayed high 12 weeks after treatment, and gut bacteria were still less diverse and clearly different at that point. Mouth bacteria changed far less. The authors say recovery is slow and more work is needed on gut support around surgery.
Catalog record
| CREATOR | Yihao Zhang, Junze Xue, Hao Lin, Kun Wang, Xiaojie Tan, Xuelong Jiao, Haitao Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32339 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |