Development, validation, and cost-effectiveness analysis of an AI-assisted three-tiered glaucoma screening model in a community-based setting: protocol for a cluster randomized controlled trial

Xiangyu Fu, Jiaying Zhang, Shanming Jiang, Xi Liu, Haotian Xiang, Xianjie Yu, Meng Wang, Yutong Liu, Li Tang · 2026

Read Development, validation, and cost-effectiveness analysis of an AI-assisted three-tiered glaucoma screening model in a community-based setting: protocol for a cluster randomized controlled trial by Xiangyu Fu, Jiaying Zhang, Shanming Jiang, Xi Liu, Haotian Xiang, Xianjie Yu, Meng Wang, Yutong Liu, Li Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13243054.txt.

Description

Xiangyu Fu and co-authors set out a trial protocol in this 2026 paper on glaucoma, an eye disease that can blind people without warning signs. China has no widely accepted screening model for it, so the team plans to build and test a three-step one for community use.

The model starts with a risk questionnaire, moves to eye checks with image reading helped by artificial intelligence, and ends with firm diagnosis at large hospitals. The trial will enrol 28,275 people across communities, split into no screening, routine screening, and tiered screening groups, with at least six years of follow-up. It will compare detection rates and costs between the groups.

Catalog record

CREATORXiangyu Fu, Jiaying Zhang, Shanming Jiang, Xi Liu, Haotian Xiang, Xianjie Yu, Meng Wang, Yutong Liu, Li Tang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42094
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13243054

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