Cytokeratin-Positive Pleomorphic Chest Wall Sarcoma Mimicking MPNST: A Case Report
Mohammad Alaa Aldakak, Ahmad Bishr Nasra, Raneem Ahmad, Hamza Alhallaq, Kinda Assoud, Hussain Chaban · 2026
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Description
Mohammad Alaa Aldakak and co-authors present a 2026 case of a chest wall sarcoma that was misread as a nerve sheath tumor. A 62-year-old carpenter arrived with persistent chest pain and a firm mass fixed deep in the chest wall. A needle biopsy suggested one tumor type, which guided initial thinking.
Surgeons removed the mass in one block with parts of three ribs and involved muscle, then rebuilt the wall with mesh and metal plates. Full tissue analysis told a different story: an undifferentiated pleomorphic sarcoma carrying an epithelial marker that widened the diagnostic confusion. One margin still held tumor, while others were clear. The authors highlight the limits of core biopsy and the need for team discussion on added local therapy.
Catalog record
| CREATOR | Mohammad Alaa Aldakak, Ahmad Bishr Nasra, Raneem Ahmad, Hamza Alhallaq, Kinda Assoud, Hussain Chaban |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |