Investigation of Esketamine Administration During Surgical Procedures for the Alleviation of Postoperative Anxiety and Depression in Adolescent Patients: A Randomized Controlled Trial
Yanhong Li, Kuangyu Zhao, Peipei Cao, Qian Wang, Kairui Li, Jun Zhou · 2026
Read Investigation of Esketamine Administration During Surgical Procedures for the Alleviation of Postoperative Anxiety and Depression in Adolescent Patients: A Randomized Controlled Trial by Yanhong Li, Kuangyu Zhao, Peipei Cao, Qian Wang, Kairui Li, Jun Zhou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13242777.txt.
Description
Yanhong Li and co-authors report a 2026 randomized trial of esketamine given during surgery to prevent anxiety and depression in adolescents. Surgery stresses teenagers, and few preventive options have been tested in this age group. Esketamine, a fast-acting anesthetic relative, also lifts mood at low doses.
Ninety-two adolescents having elective surgery received either a low dose of the drug or saline at the first incision, without knowing which. Eighty finished the study. Anxiety scores were lower in the drug group at every check across two weeks. Depression scores differed only at the final check. Inflammation markers and side effects were similar between groups. The authors note the single-center, modest sample and want multicenter confirmation.
Catalog record
| CREATOR | Yanhong Li, Kuangyu Zhao, Peipei Cao, Qian Wang, Kairui Li, Jun Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |