Association of Umbilical Cord Blood P-Selectin and PTX3 Levels with Early-Onset Sepsis in Preterm Infants with Premature Rupture of Membranes

Yong Luo, Mingyue Li, Wei Liu, Wenlong Xiu · 2026

Read Association of Umbilical Cord Blood P-Selectin and PTX3 Levels with Early-Onset Sepsis in Preterm Infants with Premature Rupture of Membranes by Yong Luo, Mingyue Li, Wei Liu, Wenlong Xiu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13242775.txt.

Description

Yong Luo and co-authors present a 2026 study of cord blood markers for early sepsis in preterm babies born after the waters broke early. Early-onset sepsis is a leading threat to such infants, and standard markers react late. Two immune-related proteins, P-selectin and PTX3, were measured in umbilical cord blood.

Babies whose mothers had prolonged membrane rupture showed higher levels than healthy controls. Levels ran higher again in the subgroup that developed sepsis, and the two markers moved together. Each marker alone sorted septic from non-septic babies well, and together they performed better than the usual inflammation tests. Gram-negative bacteria, mainly E. coli, caused most confirmed infections. The authors propose the pair for early risk checks.

Catalog record

CREATORYong Luo, Mingyue Li, Wei Liu, Wenlong Xiu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13242775

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