Progesterone is inversely associated with optic nerve sheath diameter in dogs: a cross-sectional analysis

Candemir Özcan, Ümran Akın Özcan, Kenan Çağrı Tümer, Tarik Safak · 2026

Read Progesterone is inversely associated with optic nerve sheath diameter in dogs: a cross-sectional analysis by Candemir Özcan, Ümran Akın Özcan, Kenan Çağrı Tümer, Tarik Safak (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13242484.txt.

Description

Candemir Özcan and co-authors looked for hormone links to the width of the optic nerve sheath in healthy female dogs. Their study appeared in Veterinary Research Communications in 2026. The sheath's diameter, measured by ultrasound through the orbit, serves as a stand-in for pressure inside the skull. Thirty-four dogs of varied ages and sizes had the measurement taken alongside blood tests for estradiol and progesterone.

Progesterone showed a moderate negative link with sheath diameter: dogs with higher levels tended to have narrower sheaths. Age, body mass, and estradiol showed no clear relationship with the measurement. The authors are careful to call the progesterone finding modest and in need of confirmation. Even so, it suggests hormone state belongs on the list of factors vets should weigh when reading this scan. Reference values built without that context could mislead.

Catalog record

CREATORCandemir Özcan, Ümran Akın Özcan, Kenan Çağrı Tümer, Tarik Safak
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13242484

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