Cytosolic Ca2+ mediates ATG8i-autophagy activation under osmotic stress in Arabidopsis thaliana
Luis Castillo-Olamendi, Gladys Jiménez-Nopala, Salvador Barrera-Ortiz, Ausencio Galindo, Elizabeth Cordoba, Paul Rosas-Santiago, Patricia León, Helena Porta · 2026
Read Cytosolic Ca2+ mediates ATG8i-autophagy activation under osmotic stress in Arabidopsis thaliana by Luis Castillo-Olamendi, Gladys Jiménez-Nopala, Salvador Barrera-Ortiz, Ausencio Galindo, Elizabeth Cordoba, Paul Rosas-Santiago, Patricia León, Helena Porta (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13242460.txt.
Description
Luis Castillo-Olamendi and colleagues studied how calcium signals switch on recycling inside plant cells under salt-like water stress. Their paper appeared in Planta in 2026, using the model plant Arabidopsis thaliana. When water grows scarce, plant cells break down and reuse damaged parts through autophagy. The team tracked a tagged protein called ATG8i and watched calcium levels with a glowing sensor line.
Osmotic stress triggered a calcium surge, strongest where the stem meets the root. That zone also filled with ATG8i-marked autophagosomes, the small sacs that carry cargo to be recycled. Blocking calcium entry from outside the cells weakened the response. The sacs overlapped with the endoplasmic reticulum, hinting at a targeted form of recycling for that structure. The authors conclude that calcium acts as the messenger linking water stress to this cleanup system.
Catalog record
| CREATOR | Luis Castillo-Olamendi, Gladys Jiménez-Nopala, Salvador Barrera-Ortiz, Ausencio Galindo, Elizabeth Cordoba, Paul Rosas-Santiago, Patricia León, Helena Porta |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |