Probing the habitual and compulsive-like basis of (dys)functional checking in the Observing Response Task, a rodent analogue relevant to obsessive-compulsive disorder

Luise Pickenhan, Amy L Milton · 2026

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Description

Luise Pickenhan and Amy L Milton report a 2026 rat study of compulsive-like checking behavior relevant to obsessive-compulsive disorder. Rats performed a task where a special lever lit a cue showing which reward lever was currently correct. Extra presses on that lever served no purpose and modeled dysfunctional checking.

Rats prone to chasing cues, called sign-trackers, showed more useless checking than other rats. Their checking persisted even when the link between checking and the cue was weakened, suggesting habit-driven behavior. When checking was punished with shocks, most rats stopped, yet a minority of sign-trackers kept going. The authors compare that persistence to severe human cases where checking continues despite bad consequences.

Catalog record

CREATORLuise Pickenhan, Amy L Milton
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13242449

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