Evaluation of the efficacy of rutin, rutin nanocrystals, and rutin spanlastics nanoparticles as antitumor and antioxidant drug delivery systems
Badriyah S. Alotaibi, Thanaa A. El-Masry, Maisra M. El-Bouseary, Enas I. El Zahaby, Eman Wahsh, Asmaa Saleh, Ahlam Mansour Sultan, Manal E. Alosaimi, Maysa M. F. El-Nagar · 2026
Read Evaluation of the efficacy of rutin, rutin nanocrystals, and rutin spanlastics nanoparticles as antitumor and antioxidant drug delivery systems by Badriyah S. Alotaibi, Thanaa A. El-Masry, Maisra M. El-Bouseary, Enas I. El Zahaby, Eman Wahsh, Asmaa Saleh, Ahlam Mansour Sultan, Manal E. Alosaimi, Maysa M. F. El-Nagar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13242332.txt.
Description
Alotaibi and colleagues in Riyadh packed the flavonoid rutin three ways to rescue its poor water solubility. Free rutin faced rutin nanocrystals and elastic spanlastics head-to-head. Human breast cancer cells supplied the test bed. Radical-scavenging assays gauged antioxidant power alongside cancer cell kill.
Spanlastics came out smallest, most uniform, and most stable in suspension overall. They quenched test radicals best and killed MCF-7 cells hardest. Apoptosis markers rose sharply and the cell cycle stalled in its first gap phase. The authors recommend follow-up animal studies of the winning vesicle formulation.
Catalog record
| CREATOR | Badriyah S. Alotaibi, Thanaa A. El-Masry, Maisra M. El-Bouseary, Enas I. El Zahaby, Eman Wahsh, Asmaa Saleh, Ahlam Mansour Sultan, Manal E. Alosaimi, Maysa M. F. El-Nagar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |