Organelle regulation of ferroptosis after intracerebral hemorrhage
Na Zhou, Yang Du, Yinuo Wang, Xingquan Zhao, Yi Ju · 2026
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Description
Na Zhou and co-authors reviewed organelle control of ferroptosis after brain haemorrhage in a 2026 paper. This stroke type carries high death and disability rates. Ferroptosis, an iron-driven form of cell death, has emerged as a key driver of secondary brain injury after bleeding, through iron buildup and fat damage.
The review maps how each cell part contributes: mitochondria, the endoplasmic reticulum, lysosomes, lipid droplets, peroxisomes, and the Golgi body, plus contact sites between them. Antioxidant defence breakdown sits at the centre of the process. The authors then sum up treatments that target ferroptosis from an organelle view, presenting it as a promising route for future intervention.
Catalog record
| CREATOR | Na Zhou, Yang Du, Yinuo Wang, Xingquan Zhao, Yi Ju |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |