Localized bullous pemphigoid masquerading as venous leg ulcers in a patient with chronic venous insufficiency
Alexis Perry, Saman Namazian, Tony Vu, Joshua Mervis · 2026
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Description
Alexis Perry and co-authors report a blistering disease that hid behind a common leg problem. Bullous pemphigoid is an autoimmune skin disease of older adults, marked by tense blisters. Its localized form is rare, about 2.5 in a hundred cases, and favors spots of trauma or chronic swelling.
Their patient, a 76-year-old man with diabetes, atrial fibrillation, and kidney disease, also had chronic venous insufficiency in his legs. His leg blisters were read as edema blisters and venous ulcers for some time. The true diagnosis was localized pemphigoid, triggered by the vein problem. Dupilumab plus compression brought lasting remission.
Catalog record
| CREATOR | Alexis Perry, Saman Namazian, Tony Vu, Joshua Mervis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |