Clinical trials of surgical neuromodulation therapies for epilepsy: Past, present & future
Rory J. Piper, Martin M. Tisdall · 2026
Read Clinical trials of surgical neuromodulation therapies for epilepsy: Past, present & future by Rory J. Piper, Martin M. Tisdall (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13241853.txt.
Description
Rory J. Piper and Martin M. Tisdall offer a 2026 review of clinical trials for implanted stimulation therapies in epilepsy. About a third of people with epilepsy keep having seizures on medication. Some cannot have the seizure source removed by surgery, which leaves stimulation as an alternative.
Options now include deep brain stimulation, a responsive system that reacts to seizure signals, vagus nerve stimulation, and a newer under-scalp device. The review walks through the milestone trials that shaped current practice for each option. Ongoing trials are summarized, and the authors look ahead to how future studies should be designed. Readers gain a single map of an expanding treatment field for drug-resistant epilepsy.
Catalog record
| CREATOR | Rory J. Piper, Martin M. Tisdall |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |