Long-term effectiveness of endoscopic and stool-based colorectal cancer screening strategies: a systematic review and network meta-analysis
Motoki Kaneko, Atsushi Sakuraba · 2026
Read Long-term effectiveness of endoscopic and stool-based colorectal cancer screening strategies: a systematic review and network meta-analysis by Motoki Kaneko, Atsushi Sakuraba (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13241687.txt.
Description
Motoki Kaneko and Atsushi Sakuraba publish a 2026 network meta-analysis of long-term colorectal cancer screening results. Four strategies were compared: colonoscopy, flexible sigmoidoscopy, and two stool-based tests. Trial evidence on ten-year outcomes guided the analysis.
Looking at everyone invited to screening, colonoscopy and sigmoidoscopy both lowered new cancer cases. Sigmoidoscopy and the older stool test lowered deaths from this cancer, while colonoscopy did not reach that mark in this analysis. No strategy reduced deaths overall. Among people who actually completed screening, benefits looked larger across methods. The authors advise choosing strategies with uptake and health system capacity in mind, since invitation-level effects depend on participation.
Catalog record
| CREATOR | Motoki Kaneko, Atsushi Sakuraba |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |