Clinical associations and related factors of metabolic syndrome in systemic sclerosis: results from an observational multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale)

Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Marco Minerba, Antonio Orlando, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani · 2026

Read Clinical associations and related factors of metabolic syndrome in systemic sclerosis: results from an observational multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Marco Minerba, Antonio Orlando, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13241409.txt.

Description

Liakouli and the Italian GIRRCS network measured metabolic syndrome inside a large systemic sclerosis cohort. Six hundred thirteen patients from eleven top centers enrolled at one point in time. Five hundred seventy had complete data for the study. Syndrome status followed the shared global definition from 2009.

Under nine percent met the syndrome bar, a modest share. Those patients skewed older, with far more active disease and mild lung restriction. Heart involvement, lung pressure, and advanced nailfold capillary damage all ran higher. Active disease and lung stiffness stayed linked after adjustment. Hypertension was the commonest single part.

Catalog record

CREATORVasiliki Liakouli, Giulio Forte, Piero Ruscitti, Marco Minerba, Antonio Orlando, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13241409

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