Isolated Pleural Effusion as Presentation of a Large B‐Cell Lymphoma: A Case Report and Diagnostic Considerations

Van Vlierberghe Magalie, Dewaide Rosina, Michaux Lucienne, Develter Wim, Van Aelst Sophie, Claerhout Helena · 2026

Read Isolated Pleural Effusion as Presentation of a Large B‐Cell Lymphoma: A Case Report and Diagnostic Considerations by Van Vlierberghe Magalie, Dewaide Rosina, Michaux Lucienne, Develter Wim, Van Aelst Sophie, Claerhout Helena (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13240584.txt.

Description

Van Vlierberghe and co-authors present a lymphoma that announced itself only as fluid on the lung. A 79-year-old man arrived breathless with a massive pleural effusion; scans found no tumor mass anywhere else. Fluid analysis revealed large abnormal B cells forming a single clone, with a complex extra-chromosome pattern, and tests for the usual viral drivers came back negative.

The picture best fits a newly recognized class, fluid overload-associated large B-cell lymphoma, though cousins in the effusion family overlap confusingly. He received standard R-CHOP immune-chemotherapy and stays stable with no spread. The authors stress that only the full stack of cell, molecular, and virus tests can name these lymphomas correctly, and the name steers treatment.

Catalog record

CREATORVan Vlierberghe Magalie, Dewaide Rosina, Michaux Lucienne, Develter Wim, Van Aelst Sophie, Claerhout Helena
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13240584

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