Development of Magnetic Particle–Based Chemiluminescence Immunoassays for Detecting PCV2 VLP‐ and Rep‐Specific Antibodies and Their Combined Use for Immune Evaluation and Replication‐Associated Exposure Assessment
Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge · 2026
Read Development of Magnetic Particle–Based Chemiluminescence Immunoassays for Detecting PCV2 VLP‐ and Rep‐Specific Antibodies and Their Combined Use for Immune Evaluation and Replication‐Associated Exposure Assessment by Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13240412.txt.
Description
Mingxi Gou and team build two machine-run blood tests to read pig immunity with more nuance in a 2026 study. Porcine circovirus 2 is a major swine pathogen. Standard antibody tests cannot split vaccine responses from signs that the virus is at work in a herd, so the team built a paired approach.
One test gauges antibodies against the virus shell, built as hollow virus-like particles. The next targets the protein that shows only when the virus copies itself. Both run on magnetic beads with light-based detection in a fully machine-run format. Each test agreed with standard lab tests in more than nine of ten samples, and the shell test beat the standard on sensitivity. Field samples showed the pair apart, split vaccine patterns from true exposure.
Catalog record
| CREATOR | Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |