Experimental verification of the proton range using heterogeneous animal tissue

Andrew J Boria, Chia‐Ho Hua, Thomas E Merchant, Chin‐Cheng Chen · 2026

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Description

Andrew Boria and co-authors checked proton beam range in uneven animal tissue in a 2026 study. Proton therapy stops inside the tumor, sparing tissue beyond. That gift depends on knowing exactly how far protons travel. CT numbers convert to stopping power only roughly, and tissue mix shifts the range.

The team fired protons through varied animal tissue samples. Measured ranges were set against the clinic calibration curve. Even small density shifts can move the stopping point. Modern scanning plans include safety margins for that error. Direct tissue checks show where the curve still misleads. Tighter ranges would sharpen tumor coverage.

Catalog record

CREATORAndrew J Boria, Chia‐Ho Hua, Thomas E Merchant, Chin‐Cheng Chen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13240389

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